AMCT™ Whitepaper — Version 2.0 · Feb 2026

Advanced Micronized Chelation Technology™

A next-generation oral delivery platform for GLP-1 receptor agonists and peptide biologics. AMCT™ replaces gastric disruption with controlled, biologically aligned transport mechanisms.

~200×

Lower API Dose vs. SNAC

180+ days

Sustained Observational Data

0.05–0.35 mg

Observed Daily GLP-1 Range

No fasting

Administration Requirement

Safety & Tolerability Profile

Unlike gastric pH-altering or membrane-irritating excipient systems, AMCT™ is designed to preserve epithelial integrity and physiologic function. Observational use has demonstrated no gastric mucosal injury, no clinically meaningful epithelial barrier disruption, and no dose-limiting GI toxicity attributable to the delivery system.

No Gastric Irritation

No mucosal injury attributed to delivery system

No Serious AEs

No serious adverse events observed to date

Consistent GLP-1 Profile

AEs consistent with known GLP-1 class, not delivery-specific

Table 1: Observed Safety & Tolerability — AMCT™-Enabled Oral GLP-1
System Organ ClassAdverse EventSeverityFrequencyDuration / Resolution
GastrointestinalNausea
Mild
OccasionalTransient; resolved without intervention
GastrointestinalEarly satiety / appetite suppression
Mild
CommonPersistent during active therapy
GastrointestinalAbdominal discomfort
Mild
InfrequentSelf-limited
GastrointestinalVomiting
None observed
——
GastrointestinalDiarrhea
None observed
——
MetabolicHypoglycemia
None observed†
——
Nervous systemHeadache
Mild
InfrequentTransient
General disordersFatigue
Mild
InfrequentTransient
CardiovascularClinically significant events
None observed
——
HepaticClinically significant abnormalities
None observed
——
Renal / UrinaryClinically significant abnormalities
None observed
——

† No hypoglycemia observed; consistent with GLP-1 class. Data from limited non-randomized observational use. Not intended to establish incidence rates or comparative safety.

Educational reference only. For licensed prescribers. No claims of bioequivalence or therapeutic equivalence. All prescribing decisions remain with the treating clinician. Confidential — not for patient distribution. Source: AMCT™ Whitepaper Version 2.0, Updated February 2026 · Zoom Biotech / Village Compounding Pharmacy Partnership.